Lactoferrin 17-41

CAS No. 146897-68-9

Lactoferrin 17-41( —— )

Catalog No. M30217 CAS No. 146897-68-9

This is amino acids 17 to 41 fragment of lactoferrin, known as lactoferricin B. This peptide shows anti-fungal properties in combination of other anti-fungal agents.Candida Albicans is one of the targets of the lactoferricin B.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Lactoferrin 17-41
  • Note
    Research use only, not for human use.
  • Brief Description
    This is amino acids 17 to 41 fragment of lactoferrin, known as lactoferricin B. This peptide shows anti-fungal properties in combination of other anti-fungal agents.Candida Albicans is one of the targets of the lactoferricin B.
  • Description
    This is amino acids 17 to 41 fragment of lactoferrin, known as lactoferricin B. This peptide shows anti-fungal properties in combination of other anti-fungal agents.Candida Albicans is one of the targets of the lactoferricin B.
  • In Vitro
    Lactoferrin 17-41 (Lactoferricin B) has an MIC of 30 μg/ml against E. coli ATCC 25922.Lactoferrin 17-41 significantly stimulates apoptosis of HT-29 cells and displays cytotoxic activity on HT-29 cells.Lactoferrin 17-41 variously regulats transcription of genes involved in the p53 signaling pathway, such as PMAIP-1, TP5313, and SFN.Lactoferrin 17-41 can bind LPS from Gram-negative bacteria and that it can inhibit LPS induced cytokine response in human monocytic cells. Cell Viability Assay Cell Line:HT-29 cells Concentration:50, 100, 200, 400, 800 or 1000 μg/mL Incubation Time:4, 12, 24 or 48 hours Result:More effective at inducing apoptosis at 400 μg/mL. Higher toxicity is shown at 800 μg/mL.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    GPCR/G Protein
  • Target
    Antibacterial
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    146897-68-9
  • Formula Weight
    3123.77
  • Molecular Formula
    C141H224N46O29S3
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name
    Sequence:{Phe}{Lys}{Cys}{Arg}{Arg}{Trp}{Gln}{Trp}{Arg}{Met}{Lys}{Lys}{Leu}{Gly}{Ala}{Pro}{Ser}{Ile}{Thr}{Cys}{Val}{Arg}{Arg}{Ala}{Phe} (Disulfide bridge: Cys3-Cys20)

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

Samuelsen ?, et al. Anti-complement effects of lactoferrin-derived peptides. FEMS Immunol Med Microbiol. 2004 Jun 1;41(2):141-8.
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